Raman spectroscopy - A new dawn in clinical diagnostics

Raman spectroscopy - A new dawn in clinical diagnostics

February 2017

Raman spectroscopy (RS) has shown enormous potential in sensitive and specific elucidation of latent information of a diverse array of pathophysiological conditions. This talk highlighted the application of RS in two important clinical domains, namely middle-ear pathology and alternative glycemic marker detection. Dr Pandey presented his first demonstration of distinguishing the cholesteatoma from a morphologically similar lesion called myringosclerosis. The other focal point will be on the effort in developing a RS-based objective and reagent-free assay for multiplex detection of long-term glycemic markers. These results demonstrate the path forward towards his groups clinical translation of such integrative photonics solutions.

Jeff Oleske from Andor Technology presented the benefits of Low Dark Current-Deep Depletion (LDC-DD) technology for NIR Spectroscopy. The iDus 416 CCD from Andor combines the LDC-DD sensor with a deep TE-cooled platform for high sensitivity and high resolution NIR detection.

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A facile and real-time spectroscopic method for biofluid analysis in point-of-care diagnostics
Spectroscopic Raman study of sulphate precipitation sequence in Rio Tinto mining district (SW Spain)
Crystallinity and compositional changes in carbonated apatites: Evidence from< sup> 31</sup> P solid-state NMR, Raman, and AFM analysis
Raman spectroscopy demonstrates prolonged alteration of bone chemical composition following extremity localized irradiation
A combined dielectrophoresis-Raman setup for the classification of pathogens recovered from the urinary tract
Synthesis, Characterization, and Atomistic Modeling of Stabilized Highly Pyrophoric Al (BH4) 3 Via the Formation of the Hypersalt K [Al (BH4) 4]
Environmental effects on the Raman spectra of single walled carbon nanotubes
Integrated system for combined Raman spectroscopy–spectral domain optical coherence tomography
Raman spectroscopy study of molecular hydrogen solubility in water at high pressure
Raman Microspectroscopy – A Non-Invasive Analysis Tool For Monitoring Of Collagen-Containing Extracellular Matrix Formation in a Medium-Throughput Culture System
Raman microspectroscopic and dynamic vapor sorption characterization of hydration in collagen and dermal tissue
Probing speciation inside a conducting polymer matrix by in situ spectroelectrochemistry
Picosecond spectral coherent anti-Stokes Raman scattering imaging with principal component analysis of meibomian glands
pH-induced metal-ligand cross-links inspired by mussel yield self-healing polymer networks with near-covalent elastic moduli
Optimizing Gold Nanoparticle Cluster Configurations (n 7) for Array Applications
Optimising reproducibility in low quality signals without smoothing; an alternative paradigm for signal processing
Optimal Size of Silver Nanoparticles for Surface-Enhanced Raman Spectroscopy
High Pressure Vibrational Spectroscopy of Hexahydro 1, 3, 5 Trinitro 1, 3, 5 Triazine (RDX)
Gas-phase thermometry using delayed-probe-pulse picosecond coherent anti-Stokes Raman scattering spectra of H2
Functional plant cell wall design revealed by the Raman imaging approach

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