Super Resolution Microscopy

Featured Application

Application Notes and Case Studies
General Introduction to Super Resolution

Resolution limits imposed by light diffraction have always been major obstacle in analysing microscopic images and obtaining insights into the fabric of living cells. To date, our best optical tools have only revealed structures measuring approximately 200 nm across and anything...

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Resolution limits imposed by classical light diffraction represent a major limitation in the ability to obtain meaningful insights into the fabric of living cells. Conventional optical microscopy tools have only revealed structures measuring approximately 200 nm across. Unfortunately, most...

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Light microscopy has always been suffering from the limit imposed by the Abbe′s law which manifested itself as presence of Airy disks. These structures defined the resolution of any optical systems regardless of imaging modality. For all users of microscopy systems it meant that...

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Double-helix and Super-resolution

In the past few years we have witnessed an unprecedented evolution of imaging techniques, directed at helping researchers break through what was previously regarded as an immutable optical resolution limit. Several novel super-resolution methods have made it possible to look...

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Multi-color direct STORM

Lampe et al have developed a novel variant of direct STORM (dSTORM) termed spectral demixing dSTORM (SD-dSTORM) that combines the photochemical advantages of the red emitting carbocyanine dyes with the principal of spectral demixing. Specifically, they use a novel...

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Novel insights into cell nucleus

Structured illumination microscopy has proved to be an excellent alternative to several existing microscopy techniques. Extending the capabilities of classical multi-colour fluorescence wide-field or confocal microscopic systems, it can provide sufficient resolution needed for analyses...

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The Endoplasmic Reticulum (ER), Golgi, endosomes, lysosomes, mitochondria and plasma membrane, all of which are membrane structures perform a variety of functions in eukaryotic cells. In order to accommodate these functions cellular membranes fold into various shapes...

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Multimedia Library
Application Images (14)
Publications Database
Evaluation of genetic damage in tobacco and arsenic exposed population of Southern Assam, India using buccal cytome assay and comet assay
Chloroquine-induced glioma cells death is associated with mitochondrial membrane potential loss, but not oxidative stress
Superresolution imaging of single DNA molecules using stochastic photoblinking of minor groove and intercalating dyes
Receptor–Ligand Interactions: Binding Affinities Studied by Single‐Molecule and Super‐Resolution Microscopy on Intact Cells
Super-resolution imaging of C-type lectin spatial rearrangement within the dendritic cell plasma membrane at fungal microbe contact sites
Point spread function optimization for STORM using adaptive optics
Click chemistry for the conservation of cellular structures and fluorescent proteins: ClickOx
Multiple Spatial and Kinetic Subpopulations of CaMKII in Spines and Dendrites as Resolved by Single-Molecule Tracking PALM
Micromirror structured illumination microscope for high-speed in vivo drosophila brain imaging
Optimising the signal-to-noise ratio in measurement of photon pairs with detector arrays
Statistics of twin-beam states by photon-number resolving detectors up to pump depletion
The Einstein-Podolsky-Rosen paradox in twin images
Spatial properties of twin-beam correlations at low-to high-intensity transition
Coherence properties of high-gain twin beams generated in pump-depletion regime
Quantitative single-molecule localization microscopy combined with rule-based modeling reveals ligand-induced TNF-R1 reorganization toward higher-order …
A simple method to estimate the average localization precision of a single-molecule localization microscopy experiment
TestSTORM: Simulator for optimizing sample labeling and image acquisition in localization based super-resolution microscopy
Data Analysis for Single-Molecule Localization Microscopy
Focus on Super-Resolution Imaging with Direct Stochastic Optical Reconstruction Microscopy (dSTORM)
Extracellular Monomeric Tau is Sufficient to Initiate the Spread of Tau Pathology

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