Zyla 5.5 is a large field of view, high resolution 5.5 megapixel sCMOS camera, ideal for research and OEM usage. Zyla 5.5 offers a 100 fps frame rate and ultra-low noise performance, in a light, compact design. A highly cost-effective USB 3.0 version is available, offering industry fastest speeds up to 40 fps (full frame), representing the ideal performance upgrade for your lab. NEW GPU Express works alongside SDK3 to enable simplified and optimized data transfers from camera to GPU for real time processing. Zyla for the Biologist - Click here to learn moreZyla for the Physicist - Click here to learn more True Global Exposure Zyla 5.5 CMOS camera uniquely offers both Rolling [see the video] [see the video] FIND OUT MORE
True Global Exposure Zyla 5.5 CMOS camera uniquely offers both Rolling [see the video] [see the video] FIND OUT MORE
Andor's Zyla 5.5 sCMOS camera offers high speed, high sensitivity imaging performance in a remarkably light and compact, TE cooled design. Zyla is ideally suited to many cutting-edge applications that push the boundaries of speed, offering sustained frame rate performance of up to 100 fps, faster with ROIs.
A highly cost-effective USB 3.0 version is available offering 40 fps and 1.2 e- rms read noise, representing an ideal low light 'workhorse' upgrade camera solution for both microscopy and physical science applications, in either research or OEM environments.
Rolling and Global (Snapshot) Shutter readout inherent to Zyla 5.5 ensures maximum application flexibility. Global shutter to the in particular provides an important 'freeze frame' exposure mechanism that emulates that of an interline CCD, overcoming the transient readout nature of Rolling shutter mode.
The Andor GPU Express library has been created to simplify and optimize data transfers from camera to a CUDA-enabled NVidia Graphical Processing Unit (GPU) card to facilitate accelerated GPU processing as part of the acquisition pipeline.
The Zyla 5.5 sCMOS is capable of delivering 100 fps sustained, the data streaming to PC through a high-bandwidth ‘10-tap’ Camera Link interface. A market leading, cost effective USB 3.0 version is also available, delivering 40 fps (full frame), faster from ROI.
The sCMOS sensor in Zyla 5.5 has highly parallel readout architecture. All 2560 columns possess their own Amplifier and Analogue to Digital Converter (ADC), at both the top and bottom of the column. This means that not only are all columns read out in parallel, but the readout direction of each column is split in the center, the signal from top and bottom halves.
Zyla 5.5 frame rates across different ROI sizes; 12-bit (16-bit) modes
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Andor’s ultrasensitive Zyla 5.5 sCMOS camera offers an unparalleled 1.2 electron typical read noise floor, achievable at 30 fps, representing 200MHz pixel readout. Furthermore, advancing readout to full speed has minimal impact on read noise, the Zyla 5.5 offering a typical noise value of 1.45 electron at 100 full fps. For the best CCD cameras to even approach 2 electrons noise, a readout speed of 1MHz or slower is required. This minimal detection limit renders the Zyla 5.5 sCMOS suitable for a wide variety of challenging low light imaging applications when compared to CCD cameras.
To learn more, download the Andor sCMOS Brochure to access the technical note entitled ‘Understanding Read Noise in sCMOS ’.
Zyla 5.5 offers the distinct capability to offer both Rolling shutter and Global (Snapshot) shutter readout modes within the same camera, such that the most appropriate mode can be selected dependent on application requirements.
Rolling Shutter exposure sequence (single frame)
Global Shutter sequence (single frame)
To learn more, download the Andor sCMOS Brochure to access the technical note entitled ‘Rolling and Global Shutter ’.
The Andor GPU Express library has been created to simplify and optimize data transfers from camera to a CUDA-enabled NVidia Graphical Processing Unit (GPU) card to facilitate accelerated GPU processing as part of the acquisition pipeline. GPU Express integrates easily with SDK3 for Andor sCMOS cameras, providing a user-friendly but powerful solution for management of high bandwidth data flow challenges; ideal for data intensive applications such as Light Sheet Microscopy, Super-Resolution Microscopy and Adaptive Optics.
The innovative Dual Amplifier architecture of the sCMOS sensor in Zyla 5.5 uniquely circumvents the need to choose between high or low gain amplifiers, in that signal can be sampled simultaneously by both high gain (low noise) and low gain (high capacity) amplifiers. As such, the lowest noise of the sensor can be harnessed alongside the maximum well depth, affording widest possible dynamic range. Uniquely for such a relatively small pixel design, this allows for dynamic range performance of 25,000:1 in Zyla 5.5.
High contrast image of LED illuminated picture, captured with Neo camera. The zoomed region shows pixel regions that are sampled by both high gain (low noise) and low gain (high capacity) amplifiers respectively.
To learn more, download the Andor sCMOS Brochure to access the technical note entitled ‘Dual Amplifier Dynamic Range ’.
A lot of intelligence has been directed towards delivering best image quality and uniformity in the Zyla 5.5. The FPGA stores offset compensation maps at the pixel level (as opposed to column level) for different combinations of gains and readout speeds, thus minimizing fixed pattern noise. Then, a further set of real time algorithms provide compensation for any further dynamic fluctuations. Gain compensation maps adjust for any minor differences in pixel responsivity, resulting in a Photon Response Non-Uniformity (PRNU) specification of < 0.5%.
These attributes, combined with markedly superior performance and similar pricing, places Zyla 5.5 sCMOS as the ideal camera with which to upgrade from existing interline CCDs.
Andor’s Dynamic Baseline Clamp affords superior background image quality (Dark image, Rolling Shutter, 10 ms exposure)
Column structure reduction algorithm, inherent to Zyla and Neo sCMOS cameras, minimizing fixed pattern column-level noise from the low gain (high capacity) channel
The Dynamic Baseline Clamp was developed by Andor specifically for their sCMOS cameras. This real time algorithm uses available dark reference pixels on either side of each row of the sensor to compensate for any real time variation of the baseline (bias) offset.
Andor’s Zyla 5.5 sCMOS camera comes equipped with an in-built FPGA filter that operates in real time to reduce the frequency of occurrence of high noise pixels. This real time filter corrects for pixels that are above 5 electrons and would otherwise appear as spurious ‘salt and pepper’ noise spikes in the image.
The appearance of such noisy pixels is analogous to the situation of Clock Induced Charge (CIC) noise spikes in EMCCD cameras, in that it is due to the fact that we have significantly reduced the noise in the bulk of the sensor that the remaining small percentage of spuriously high noise pixels can become an aesthetic issue. The filter employed dynamically identifies such high noise pixels and replaces them with the mean value of the neighbouring pixels.
Demonstration of effect of Spurious Noise Filter on a dark image, 20 ms exposure time, 560MHz readout speed.
Andor’s Zyla 5.5 sCMOS offers an FPGA generated hardware timestamp, coincident to the end of exposure with 25 nanosecond accuracy, essential to maintain accurate kinetic information relating to image capture.
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JULY 8, 2015 - Andor Technology are delighted to have partnered with Prof. Tim Stasevich (Biochemistry & Molecular Biology, Colorado State University) to present a novel approach to imaging protein dynamics in living cells.
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